Bupropion: What is it?

World of translation : Medicine
, 14:28

Bupropion"Bupropion" is a generic of the popular "Ziban" abroad, a drug that makes it easier to get out of smoking. Bupropion, like Ziban, does not have a pharmacological registration in the Russian Federation. This means that you can not get a prescription and buy it in pharmacies. Sold "Bupropion" only in online pharmacies, but this means that the entire responsibility in the event of side effects is borne by the buyer.

Domestic online pharmacies offer for sale "Bupropion", "Nosnoq", "Bupron". The main active substance of these drugs is bupropion, a full analog of bupropion, which is part of "Ziban". Such analogues are called "generics", they go through all the necessary pharmacological, biological and clinical studies. Due to the fact that generics are not produced under brand names in conventional pharmaceutical enterprises, their cost is lower than the cost of original drugs, and their effectiveness is equivalent to the originals. By the way, if you want to know how much does bupropion cost without insurance you have to visit genericinfo.org.


Tablets are white or blue, the dose of the active substance is 75, 100 and 150 mg. Tablets are bitter in taste, have a slight anesthetic effect on the oral mucosa. Tablets "Bupropion" easily divided into the risk, deposited in the middle, quickly dissolve in the water.

Pharmachologic effect

Bupropion is an antidepressant of the second generation, a selective inhibitor of re-uptake of catecholamines. Its effectiveness as an antinicotinic drug is based on the suppression of psychological dependence on nicotine (nicotine dependence), as well as on the immediate antidepressant effect, which reduces the negative manifestations that appear in the process of weaning from smoking.


The main and auxiliary medicine for the treatment of nicotine addiction.


"Bupropion" can not be used if the following medications are taken:

  • any other antidepressants, including MAO inhibitors (Moclobenide, Iproniazide, Fenelzin, Prozac, Amitriptyline);
  • anxiolytics (Alprazolam, Xanax, Triazolam);
  • glucocorticoids (steroids), including externally in the form of ointments, creams (prednisolone, hydrocortisone and others);
  • some antibiotics (tsiprolet, ciprofloxacin and the like);
  • beta-blockers used in the treatment of hypertension and cardiac drugs;
  • antiparkinsonian drugs;
  • insulin and hypoglycemic oral preparations.

You can not use "Bupropion" suffering from epilepsy of any form, as well as those who had convulsions regardless of their genesis (febrile, neurotic, after a head injury). Do not appoint Bupropion to persons younger than 18 and over 60, pregnant and lactating, as well as suffering from diabetes, chronic liver and kidney disease, Parkinson's disease, Alzheimer's disease, cancer and autoimmune diseases, a severe allergy requiring medical supervision.

Dosing and Administration

The first 6 days are taken on 1 tablet of 150 mg (or the appropriate number of tablets of lower dosage) once a day, regardless of the meal. From 7 days, take 1 tablet twice a day.

Tablets can not be chewed, not crushed, washed down with at least ½ cup of water.

The full course of treatment is 7 weeks.

In the middle of the second week of admission, it is necessary to appoint a day in which smoking will be completely discontinued. After that, the pills take place as usual. Do not change the dose, even if it seems that the drug is not effective enough.

Adverse Events

Similar to those of most antidepressants. It is dry mouth, abdominal pain, stool disorders. Possible drowsiness or excitability, limb tremor (trembling), ataxia (gait unsteadiness), dizziness, mood swings (from tearfulness to fury), decreased libido, changes in appetite. There were cases of skin itch or skin rash, acne rashes.

Most side effects occur within the first 7-10 days of admission, however, if they change into chronic form or are too severe, and if there have been any changes in the state of health, sensations, reactions during the Bupropion administration, to the doctor, having told, what preparation was accepted ("Bupropion") and for what purpose.

Additional instructions

Smoking and taking Bupropion are not mutually exclusive. To start taking "Bupropion" should be in the period of smoking - this increases the effectiveness of the drug.

You should not change the standard dosage of the drug yourself, and in case of doubt - consult a doctor.

The admission of "Bupropion" is strictly forbidden to persons with suicidal attempts and thoughts in the anamnesis, as well as those suffering from epilepsy.

Author: World of translation
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